Direct answer
Choose based on three things: what your current team can actually build and ship in, what will scale to your realistic next milestone without a rewrite, and what minimizes infrastructure decisions before product-market fit.
Do not optimize for engineering recruiting before you have revenue. Do not choose an enterprise stack at pre-seed scale.
Decision checklist
- Who is building it — a solo founder, a small team, or a mix of AI tools and contractors?
- What is the MVP? Does it need real-time features, complex auth, payments, file storage?
- What is the deploy target — web, mobile, or both?
- Are there compliance or data residency requirements?
- What managed services eliminate whole categories of infrastructure work?
A sensible default for 2025–2026
For most web-first SaaS products: TanStack Start or Next.js + Supabase + Cloudflare or Vercel + Stripe. Build it in Lovable or Cursor to accelerate. You can swap any layer later without throwing away the others.